Hyposalivation in Down Syndrome: Calcium Signaling and a New Paradigm of Preventive Care

Reduced salivary flow is a recognized clinical feature of Down syndrome, but its underlying biological mechanisms have long remained unclear. A new preclinical study now offers a molecular explanation — and potentially, a therapeutic direction. Researchers using an established mouse model of Down syndrome confirmed a significant reduction in salivation along with inflammatory changes in […]

Miniature intraoral robot: micrometer precision and reconceptualization of preparation paradigm

Swiss researchers have developed a prototype robot that could fundamentally change the predictability and precision of tooth preparation. In an interview with Dental Tribune International, Professor Ronald Jung from the University of Zurich discusses the clinical potential of the device and the technical obstacles to its implementation in practice. The device, named MIR (miniature intra-oral […]

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