{"id":23713,"date":"2026-07-15T12:47:17","date_gmt":"2026-07-15T09:47:17","guid":{"rendered":"https:\/\/otexe.com\/?p=23713"},"modified":"2026-07-15T12:47:17","modified_gmt":"2026-07-15T09:47:17","slug":"the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy","status":"publish","type":"post","link":"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/","title":{"rendered":"The protein target Mfa1 in periodontics: molecular mechanism and antibacterial intervention strategy"},"content":{"rendered":"<p>Research has shown that blocking a key bacterial appendage can prevent plaque formation, gum inflammation, and associated complications. The ability of <strong><em>Porphyromonas gingivalis<\/em><\/strong> to colonize the oral cavity largely depends on a short surface filament that helps the pathogen attach to other bacteria, establish itself within biofilms, and evade recognition by the host immune system.<\/p>\n<h2>Mechanism of Mfa filament formation and potential therapeutic targets<\/h2>\n<p>A new study conducted in Japan has elucidated the mechanism of filament formation and identified several potential targets for therapeutic intervention. <strong>The filament, known as Mfa pilus, consists of multiple copies of the Mfa1 protein.<\/strong> Scientists found that even minor alterations at one end of Mfa1 prevent filament formation, which theoretically could limit the ability of <strong><em>P. gingivalis<\/em><\/strong> to colonize.<\/p>\n<h2>The role of calcium in immune surveillance evasion<\/h2>\n<p>A separate region of the filament serves to evade immune surveillance. When the ability of this region to bind calcium was disrupted, cultured human cells demonstrated <strong>an enhanced inflammatory response<\/strong> \u2014 indicating that <strong>calcium binding facilitates the pathogen&#8217;s escape from innate immunity.<\/strong> The obtained data open new perspectives for the development of antimicrobial agents that disrupt the pathogen&#8217;s evasive mechanisms.<\/p>\n<h2>Interaction with commensal microbiota and formation of polymicrobial biofilms<\/h2>\n<p>Researchers identified the localization and structure of the Mfa1 region responsible for binding to the surface protein of <strong><em>Streptococcus gordonii<\/em><\/strong> \u2014 an early colonizer of tooth surfaces. Since this interaction promotes the development of polymicrobial biofilms, the obtained data may serve as a basis for the development of molecules that disrupt bacterial adhesion and prevent biofilm maturation at early stages of its formation.<\/p>\n<h2>Experimental evidence of efficacy and translational potential<\/h2>\n<p>The prospects for therapeutic application are supported by recent studies: <strong>antibodies against Mfa1 reduce bacterial load and alveolar bone loss<\/strong> in rat experiments. Given the growing evidence base on the association of <strong><em>P. gingivalis<\/em> with systemic diseases<\/strong> \u2014 including cardiovascular disease, diabetes mellitus, and Alzheimer&#8217;s disease \u2014 drugs developed on the basis of these results may have significance beyond dentistry and open possibilities for the prevention and treatment of systemic complications of periodontal infection.<\/p>\n<h2>Source<\/h2>\n<p><a href=\"https:\/\/www.dental-tribune.com\/news\/study-reveals-a-potential-new-target-for-periodontal-disease-treatment\/\">Original publication<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Research has shown that blocking a key bacterial appendage can prevent plaque formation, gum inflammation, and associated complications. The ability of Porphyromonas gingivalis to colonize the oral cavity largely depends on a short surface filament that helps the pathogen attach to other bacteria, establish itself within biofilms, and evade recognition by the host immune system. [&hellip;]<\/p>\n","protected":false},"author":20,"featured_media":23712,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"pmpro_default_level":"","footnotes":""},"categories":[240],"tags":[],"class_list":["post-23713","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-scientific-articles","pmpro-has-access"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The protein target Mfa1 in periodontics: molecular mechanism and antibacterial intervention strategy - OTEXE<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The protein target Mfa1 in periodontics: molecular mechanism and antibacterial intervention strategy - OTEXE\" \/>\n<meta property=\"og:description\" content=\"Research has shown that blocking a key bacterial appendage can prevent plaque formation, gum inflammation, and associated complications. The ability of Porphyromonas gingivalis to colonize the oral cavity largely depends on a short surface filament that helps the pathogen attach to other bacteria, establish itself within biofilms, and evade recognition by the host immune system. [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/\" \/>\n<meta property=\"og:site_name\" content=\"OTEXE\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/otexeworld\/reviews\" \/>\n<meta property=\"article:published_time\" content=\"2026-07-15T09:47:17+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/otexe.com\/wp-content\/uploads\/2026\/07\/study-reveals-a-potential-new-target-for-periodontal-disease-treatment.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"627\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"news bot\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@otexeworld\" \/>\n<meta name=\"twitter:site\" content=\"@otexeworld\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"news bot\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/\"},\"author\":{\"name\":\"news bot\",\"@id\":\"https:\/\/otexe.com\/en\/#\/schema\/person\/9140d95fa9a582da764836aeeea66419\"},\"headline\":\"The protein target Mfa1 in periodontics: molecular mechanism and antibacterial intervention strategy\",\"datePublished\":\"2026-07-15T09:47:17+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/\"},\"wordCount\":356,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/otexe.com\/en\/#organization\"},\"image\":{\"@id\":\"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/otexe.com\/wp-content\/uploads\/2026\/07\/study-reveals-a-potential-new-target-for-periodontal-disease-treatment.jpg\",\"articleSection\":[\"Scientific articles\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/\",\"url\":\"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/\",\"name\":\"The protein target Mfa1 in periodontics: molecular mechanism and antibacterial intervention strategy - OTEXE\",\"isPartOf\":{\"@id\":\"https:\/\/otexe.com\/en\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/otexe.com\/wp-content\/uploads\/2026\/07\/study-reveals-a-potential-new-target-for-periodontal-disease-treatment.jpg\",\"datePublished\":\"2026-07-15T09:47:17+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#primaryimage\",\"url\":\"https:\/\/otexe.com\/wp-content\/uploads\/2026\/07\/study-reveals-a-potential-new-target-for-periodontal-disease-treatment.jpg\",\"contentUrl\":\"https:\/\/otexe.com\/wp-content\/uploads\/2026\/07\/study-reveals-a-potential-new-target-for-periodontal-disease-treatment.jpg\",\"width\":1200,\"height\":627},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Main\",\"item\":\"https:\/\/otexe.com\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Uncategorized\",\"item\":\"https:\/\/otexe.com\/en\/category\/uncategorized\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"The protein target Mfa1 in periodontics: molecular mechanism and antibacterial intervention strategy\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/otexe.com\/en\/#website\",\"url\":\"https:\/\/otexe.com\/en\/\",\"name\":\"OTEXE\",\"description\":\"Is a community where the best minds in dentistry are creating the future of the industry\",\"publisher\":{\"@id\":\"https:\/\/otexe.com\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/otexe.com\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/otexe.com\/en\/#organization\",\"name\":\"Otexe\",\"url\":\"https:\/\/otexe.com\/en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/otexe.com\/en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/otexe.com\/wp-content\/uploads\/2025\/07\/logo.png\",\"contentUrl\":\"https:\/\/otexe.com\/wp-content\/uploads\/2025\/07\/logo.png\",\"width\":697,\"height\":697,\"caption\":\"Otexe\"},\"image\":{\"@id\":\"https:\/\/otexe.com\/en\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/otexeworld\/reviews\",\"https:\/\/x.com\/otexeworld\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/otexe.com\/en\/#\/schema\/person\/9140d95fa9a582da764836aeeea66419\",\"name\":\"news bot\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/otexe.com\/en\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/126946fb002d82862ee4daf1c3c87cd017acab2d58cb90a684793b86e7347e3d?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/126946fb002d82862ee4daf1c3c87cd017acab2d58cb90a684793b86e7347e3d?s=96&d=mm&r=g\",\"caption\":\"news bot\"},\"url\":\"https:\/\/otexe.com\/en\/author\/news-bot\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"The protein target Mfa1 in periodontics: molecular mechanism and antibacterial intervention strategy - OTEXE","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/","og_locale":"en_US","og_type":"article","og_title":"The protein target Mfa1 in periodontics: molecular mechanism and antibacterial intervention strategy - OTEXE","og_description":"Research has shown that blocking a key bacterial appendage can prevent plaque formation, gum inflammation, and associated complications. The ability of Porphyromonas gingivalis to colonize the oral cavity largely depends on a short surface filament that helps the pathogen attach to other bacteria, establish itself within biofilms, and evade recognition by the host immune system. [&hellip;]","og_url":"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/","og_site_name":"OTEXE","article_publisher":"https:\/\/www.facebook.com\/otexeworld\/reviews","article_published_time":"2026-07-15T09:47:17+00:00","og_image":[{"width":1200,"height":627,"url":"https:\/\/otexe.com\/wp-content\/uploads\/2026\/07\/study-reveals-a-potential-new-target-for-periodontal-disease-treatment.jpg","type":"image\/jpeg"}],"author":"news bot","twitter_card":"summary_large_image","twitter_creator":"@otexeworld","twitter_site":"@otexeworld","twitter_misc":{"Written by":"news bot","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#article","isPartOf":{"@id":"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/"},"author":{"name":"news bot","@id":"https:\/\/otexe.com\/en\/#\/schema\/person\/9140d95fa9a582da764836aeeea66419"},"headline":"The protein target Mfa1 in periodontics: molecular mechanism and antibacterial intervention strategy","datePublished":"2026-07-15T09:47:17+00:00","mainEntityOfPage":{"@id":"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/"},"wordCount":356,"commentCount":0,"publisher":{"@id":"https:\/\/otexe.com\/en\/#organization"},"image":{"@id":"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#primaryimage"},"thumbnailUrl":"https:\/\/otexe.com\/wp-content\/uploads\/2026\/07\/study-reveals-a-potential-new-target-for-periodontal-disease-treatment.jpg","articleSection":["Scientific articles"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/","url":"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/","name":"The protein target Mfa1 in periodontics: molecular mechanism and antibacterial intervention strategy - OTEXE","isPartOf":{"@id":"https:\/\/otexe.com\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#primaryimage"},"image":{"@id":"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#primaryimage"},"thumbnailUrl":"https:\/\/otexe.com\/wp-content\/uploads\/2026\/07\/study-reveals-a-potential-new-target-for-periodontal-disease-treatment.jpg","datePublished":"2026-07-15T09:47:17+00:00","breadcrumb":{"@id":"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#primaryimage","url":"https:\/\/otexe.com\/wp-content\/uploads\/2026\/07\/study-reveals-a-potential-new-target-for-periodontal-disease-treatment.jpg","contentUrl":"https:\/\/otexe.com\/wp-content\/uploads\/2026\/07\/study-reveals-a-potential-new-target-for-periodontal-disease-treatment.jpg","width":1200,"height":627},{"@type":"BreadcrumbList","@id":"https:\/\/otexe.com\/en\/the-protein-target-mfa1-in-periodontics-molecular-mechanism-and-antibacterial-intervention-strategy\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Main","item":"https:\/\/otexe.com\/en\/"},{"@type":"ListItem","position":2,"name":"Uncategorized","item":"https:\/\/otexe.com\/en\/category\/uncategorized\/"},{"@type":"ListItem","position":3,"name":"The protein target Mfa1 in periodontics: molecular mechanism and antibacterial intervention strategy"}]},{"@type":"WebSite","@id":"https:\/\/otexe.com\/en\/#website","url":"https:\/\/otexe.com\/en\/","name":"OTEXE","description":"Is a community where the best minds in dentistry are creating the future of the industry","publisher":{"@id":"https:\/\/otexe.com\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/otexe.com\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/otexe.com\/en\/#organization","name":"Otexe","url":"https:\/\/otexe.com\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/otexe.com\/en\/#\/schema\/logo\/image\/","url":"https:\/\/otexe.com\/wp-content\/uploads\/2025\/07\/logo.png","contentUrl":"https:\/\/otexe.com\/wp-content\/uploads\/2025\/07\/logo.png","width":697,"height":697,"caption":"Otexe"},"image":{"@id":"https:\/\/otexe.com\/en\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/otexeworld\/reviews","https:\/\/x.com\/otexeworld"]},{"@type":"Person","@id":"https:\/\/otexe.com\/en\/#\/schema\/person\/9140d95fa9a582da764836aeeea66419","name":"news bot","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/otexe.com\/en\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/126946fb002d82862ee4daf1c3c87cd017acab2d58cb90a684793b86e7347e3d?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/126946fb002d82862ee4daf1c3c87cd017acab2d58cb90a684793b86e7347e3d?s=96&d=mm&r=g","caption":"news bot"},"url":"https:\/\/otexe.com\/en\/author\/news-bot\/"}]}},"_links":{"self":[{"href":"https:\/\/otexe.com\/en\/wp-json\/wp\/v2\/posts\/23713","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/otexe.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/otexe.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/otexe.com\/en\/wp-json\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/otexe.com\/en\/wp-json\/wp\/v2\/comments?post=23713"}],"version-history":[{"count":2,"href":"https:\/\/otexe.com\/en\/wp-json\/wp\/v2\/posts\/23713\/revisions"}],"predecessor-version":[{"id":23715,"href":"https:\/\/otexe.com\/en\/wp-json\/wp\/v2\/posts\/23713\/revisions\/23715"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/otexe.com\/en\/wp-json\/wp\/v2\/media\/23712"}],"wp:attachment":[{"href":"https:\/\/otexe.com\/en\/wp-json\/wp\/v2\/media?parent=23713"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/otexe.com\/en\/wp-json\/wp\/v2\/categories?post=23713"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/otexe.com\/en\/wp-json\/wp\/v2\/tags?post=23713"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}